Influence of Extracorporeal Circulation on Platelet Function of Patients Undergoing Cardiac Surgery

Goethe University

Status: Completed

Conditions: Acquired Platelet Function Disorder

Treatments: Device: Multiple electrode aggregometry analyses (Multiple Electrode Aggregometry, Multiplate(R), Verum Diagnostica, Munich, Germany)

Study type: Observational

Funder types: Other

Identifiers

NCT01354847

MEAECC

Details and patient eligibility

About

This study is planned to investigate the relationship between duration of extracorporeal circulation and the extent of (acquired) platelet dysfunctions in patients undergoing cardiac surgery.

Full description

Patients undergoing complex cardiac surgery are planned to be included. At several intra- and postoperative measuring point, blood is drawn for multiple electrode aggregometry to investigate ex-vivo platelet aggregation as a surrogate for platelet function.

Transfusion rate of allogenic blood products as well as postoperative blood loss is planned to be recorded.

Enrollment: 25 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• duration of extracorporeal circulation > 120 min

Exclusion criteria

• pregnancy

Trial design

25 participants in 1 patient group

cardiac surgery patients

Description:

cardiac surgery patients scheduled for elective complex cardiac surgery

Treatment:

Device: Multiple electrode aggregometry analyses (Multiple Electrode Aggregometry, Multiplate(R), Verum Diagnostica, Munich, Germany)