Influence of Fluid Challenge on End-Expiratory Lung Impedance in Mechanically Ventilated Patients Monitored With Electrical Impedance Tomography

University Hospital Schleswig-Holstein (UKSH)

Status: Completed

Conditions: Respiratory Failure; Circulatory Failure; Fluid Overload; Fluid Responsiveness

Treatments: Other: Fluid Challenge

Study type: Observational

Funder types: Other

Identifiers

NCT02992002

EIT Fluid Challenge

Details and patient eligibility

About

The study investigates the influence of a clinically indicated fluid challenge on end-expiratory lung impedance, assessed by electrical impedance tomography (EIT). EIT data will be collected before, during and after infusion of 500 ml of crystalloid solution in mechanically ventilated patients on an operative intensive care unit.

Enrollment: 25 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients on mechanical ventilation
• clincial decision to monitor regional ventilation with electrical impedance tomography
• clinical indication for fluid challenge
• established cardiac output monitoring with transpulmonary thermodilution

Exclusion criteria

• age < 18 years
• open lung injuries
• instable injury of spine or cranium
• thoracic metal implants
• body mass index > 35