Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease

Region Skane

Status: Completed

Conditions: Carbon Dioxide; Pulmonary Gas Exchange

Treatments: Other: Altered breath

Study type: Interventional

Funder types: Other

Identifiers

NCT01686984

2012/381

Details and patient eligibility

About

The purpose of this study is to investigate how inspiratory flow pattern influences CO2 elimination in people without primary lung disease.

The hypothesis is that a long mean distribution time, caused by a long postinspiratory pause and high end-inspiratory flow, will promote CO2 exchange in the alveoli.

Enrollment: 8 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• No known primary lung disease

Exclusion criteria

• Primary lung disease

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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8 participants in 1 patient group

Altered breath

Experimental group

Description:

The group where the investigators alter the inspiratory and expiratory aspects of a ventilated breath.

Treatment:

Other: Altered breath