Influence of Intraoperative Fluid Balance on the Incidence of Adverse Events in Pediatric Cardiac Surgery

CHU Brugmann University Hospital

Status: Completed

Conditions: Surgery; Congenital Heart Disease in Children; Fluid Overload

Treatments: Drug: Fluid balance

Study type: Observational

Funder types: Other

Identifiers

NCT05142046

CHUB_PED_Liquids-Cardiac

Details and patient eligibility

About

The intraoperative fluid balance during pediatric cardiac surgery is a very sensitive parameter given the low circulating volume and the complexity of anesthetic management but might be deleterious if inadequately managed. The hypothesis is that a highly positive intraoperative fluid balance increases the incidence of adverse events in the short and long term.

A retrospective observational study including all consecutive children admitted for cardiac surgery with cardiopulmonary bypass (CPB) from 2008 to 2018 in a tertiary children's hospital will be performed. A multivariate analysis will be carried out to study the effect of the fluid balance on the incidence of adverse events.

Enrollment: 1,400 patients

Sex: All

Ages: Under 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged 0-16 years and
• Cardiac surgery with cardiopulmonary bypass and
• operated between 2008 and 2018 at the Queen Fabiola University Children's Hospital (tertiary children's hospital)

Exclusion criteria

• ASA (American Society of Anesthesiologists) score of 5
• Jehovah's Witnesses
• incomplete hospital record

Trial design

1,400 participants in 1 patient group

Pediatric cardiac surgery

Description:

The group consists of all the children who undergo cardiac surgery in our institution from 2008 to 2018. The age limit was from birth to 16 years old.

Treatment:

Drug: Fluid balance