Influence of Mango Intake of Skin Health in Postmenopausal Women (MSS)

University of California (UC) Davis

Status

Completed

Conditions

Skin Red

Wrinkle

Treatments

Other: 16 weeks mango intake

Study type

Interventional

Funder types

Other

Identifiers

NCT03590756

1185928

Details and patient eligibility

About

This study aims to investigate the effects on 16 weeks of mango intake on skin health in postmenopausal women. Half of the participants will receive 85g portions of mangoes while the other half receive 250g portions of mangos. Participants will be instructed to consume the specific portion 4 times a week, for a total duration of 16 weeks.

Full description

Mangoes are rich in carotenoids, flavonoids, vitamins and other active phytochemicals such as resistant starches. Although a role of mangoes in skin health has long been advocated in traditional medicine, little scientific research has been conducted.

We hypothesize that 85g (0.5 cups) of mango intake for 16 weeks will have minimal impact on skin health, while 250g (1.5 cups) of mango intake will produce significant benefits.

Enrollment

36 patients

Sex

Female

Ages

50 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Postmenopausal
Fitzpatrick skin type I and II
BMI 18.5 - 35.0 kg/m2
Normal blood levels in the comprehensive metabolic panel, or values slightly out of range as approved by the study physician

Exclusion criteria

Allergic to mangoes
Fruit consumption of 2 or more cups per day
Vegetable consumption of 3 or more cups per day for females
Fruit juice consumption of more than 1 cup per day
Self-reported malabsorption
Currently taking regular prescription drugs i.e. statins, thyroid, anti-inflammatory drugs
Had any medical or cosmetic procedures such as laser resurfacing or plastic surgery to the face within the last 6 months, including botulinum toxin, dermal fillers, collagen or other similar cosmetic procedure
Autoimmune photosensitive condition or known genetic condition with a deficiency in collagen production (such as Ehler-Danlos)
Smoking (current smoker, smoked within the past year, former smokers with greater than a 20 pack-year history of smoking within the past 20 years.
Indications of substance or alcohol abuse
Unwillingness to discontinue high antioxidant supplements during washout and interventions