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Influence of Meal Skipping on Macronutrient Oxidation and Glucose Metabolism Under Isocaloric Conditions

U

University of Hohenheim

Status

Completed

Conditions

Healthy

Treatments

Behavioral: Dinner skipping
Behavioral: Breakfast skipping

Study type

Interventional

Funder types

Other

Identifiers

NCT02635139
MealSkipping

Details and patient eligibility

About

Aim of the study is to investigate the impact of meal skipping (breakfast or dinner skipping) on the regulation of glucose metabolism and macronutrient balance (protein/fat/carbohydrate intake vs. -oxidation). An isoenergetic diet with 3 conventional meals (breakfast, lunch, dinner) serves as a control.

Full description

The duration of the study is 7 days including 3 days with controlled diet and 4 days (including 5 nights) in a metabolic chamber at the Institute of Nutritional Medicine at the University of Hohenheim.

The study phase in the metabolic chamber consists of (i) 1 day with 3 meals/day = baseline day, (ii) 1 day with breakfast skipping, (iii) 1 day with dinner skipping, (iv) 1 washout day where the subjects leave the chamber between 7 a.m. until 7 p.m..

Beginning on the 3rd study day macronutrient and energy intake as well as the fasting periods are kept constant. To achieve comparable conditions the washout day is setted before the baseline day.

Enrollment

17 patients

Sex

All

Ages

20 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • healthy
  • not obese (BMI<30)

Exclusion criteria

  • food allergy
  • smoking
  • alternative nutrition habits
  • chronic disease
  • regular medication intake
  • claustrophobia

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

17 participants in 2 patient groups

Breakfast Skipping
Experimental group
Description:
Effect of breakfast skipping on metabolism
Treatment:
Behavioral: Breakfast skipping
Dinner Skipping
Experimental group
Description:
Effect of dinner skipping on metabolism
Treatment:
Behavioral: Dinner skipping

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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