Influence of Microfiltered-seawater Supplementation and Variable Resistance Training in Blood Pressure, Oxidative Stress, Hepatic, and Renal Biomarkers in Older Women

University of Valencia

Status: Completed

Conditions: Hepatic Impairment; Oxidative Stress; Renal Disease; Blood Pressure

Treatments: Dietary Supplement: Resistance training + deep sea water; Dietary Supplement: Control + Placebo; Dietary Supplement: Control + deep sea water; Dietary Supplement: Resistance training + Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT06600243

H1414072784009

Details and patient eligibility

About

This study was conducted to investigate the effects of the intake of deep sea water prior to resistance training on blood pressure, oxidative stress and hepatic and renal variables in older women.

Full description

This study was a 32 weeks, double-blinded, randomized, placebo-controlled trial.

Enrollment: 109 patients

Sex: Female

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• (i) women aged ≥65years
• (ii) able to climb 10 stairs without pause and walk 100m without a walker
• (iii) score above 23 points in the mini-mental state examination
• (iv) <1h of physical activity per week throughout the six months before the study
• (v) possess a medical certificate of aptitude to carry out physical activity

Exclusion criteria

Participants who had suffered:

• (i) any type of musculoskeletal, cardiovascular, hepatic, renal, pulmonary, neurological, or neuromuscular injury or disorder and/or
• (ii) taking any type of drug/supplement that may alter the results of the study (e.g., vitamin C, vitamin E, estrogens, beta-blockers, calcitonin, steroid hormones, etc.)
• (iii) changes in body weight of more than 10% in the year prior to the study
• (iv) have a severe hearing or visual impairment
• (v) participate in another research project (within the last six months) involving an exercise, dietetic and/or pharmaceutical intervention

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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109 participants in 4 patient groups, including a placebo group

Resistance training + deep sea water

Experimental group

Description:

Resistance training with elastic bands prior intake of deep sea water (20ml) twice weekly during 32 weeks.

Treatment:

Dietary Supplement: Resistance training + deep sea water

Resistance training + Placebo

Active Comparator group

Description:

Resistance training with elastic bands prior placebo water (20ml) twice weekly during 32 weeks.

Treatment:

Dietary Supplement: Resistance training + Placebo

Control + Deep sea water

Active Comparator group

Description:

No exercise and intake of deep sea water (20ml) twice weekly during 32 weeks.

Treatment:

Dietary Supplement: Control + deep sea water

Control + Placebo

Placebo Comparator group

Description:

No exercise and intake of placebo water (20ml) twice weekly during 32 weeks.

Treatment:

Dietary Supplement: Control + Placebo