Influence of Nutrition on Nasal and Bronchial Affliction in Patients With Allergy on Grass-Pollen

Johann Wolfgang Goethe University Hospital

Status: Completed

Conditions: Bronchial Asthma; Bronchial Hyperreactivity; Hypersensitivity; Allergy

Treatments: Other: inhalative specific bronchial provocation with grass-pollen

Study type: Interventional

Funder types: Other

Identifiers

NCT00519740

214/06/FFM

Details and patient eligibility

About

The study is meant to observe the influence of nutrition on nasal and bronchial discomfort in patients with allergy on grass pollen after specific bronchial provocation. Therefore, the investigators will record the patients' nutrition habits and measure the blood level of long chained polyunsaturated fatty-acids.

Enrollment: 120 patients

Sex: All

Ages: 12 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age >12 and <45 years
• informed consent
• Known allergy on grass-pollen

Exclusion criteria

• age <12 and >45 years
• Clinical asthma requiring regular inhalation
• vital capacity >80%
• FEV1 < 75%
• Chronic disease
• pregnancy
• Inhalative or systemic steroid use
• substance abuse
• incapability of understanding the study's purpose and performance

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)