Influence Of Nutritional Status Of Patients In The Intensive Care Output On Long Term Fate (FEEDING)

University Hospital, Clermont-Ferrand

Status: Unknown

Conditions: Nutritional Status at the Release of ICU.

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01750671

CHU-0127

Details and patient eligibility

About

It is established that the surviving patients after a stay in the ICU are characterized by frequent malnutrition and morbidity and mortality. The main goal of this work is to study the relationship between nutritional statuses during ICU hospitalization, whatever its determinants, and quality of life, morbidity and mortality at one year.

The hypothesis of the study is that the presence of under nutrition is responsible for a 10% increase in crude mortality at one year (which would be respectively 30% for malnourished patients and 20% for non-malnourished patients).

Full description

This is a multicenter cohort study of a 30-month follow-up on patients after a stay in ICU.

Nutritional parameters and evaluation of the quality of life will be collected during hospitalization and output during a visit to the Clinical Research Associate at 6 months and one year. Survival will be also noted. These parameters will be studied in comparative patients malnourished and non-malnourished.

Enrollment: 680 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of both sexes, age greater than or equal to 18 years

  • Hospitalized more than 72 hours in the ICU

  • Requiring at least one support organ failure:

    1. Ventilatory support (invasive or noninvasive)
    2. Administration of catecholamines
    3. Extrarenal purification whatever technique

  • Affiliated to a social security system

  • Having given free, informed written consent

Exclusion criteria

• Patients with end-stage disease or for which a limitation of care was decided

  • Pregnant women
  • Patients with minor or under guardianship
  • Incapacitated adults and psychiatric inpatients