Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension

University Hospital, Strasbourg, France

Status: Terminated

Conditions: Hypertension; Chronic Periodontitis

Treatments: Other: echo Doppler lower limbs

Study type: Observational

Funder types: Other

Identifiers

NCT02394860

5883

Details and patient eligibility

About

The aim of this study is to assess the influence of the severity of chronic periodontitis on hemodynamic parameters in hypertensive patients.Secondary purposes of this protocol is to identify evolution of several biomarkers and correlate the clinical situation with oral microflora.

Enrollment: 76 patients

Sex: Male

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• -Men- >40 years
• moderate and severe generalized chronic periodontitis
• Former diagnosis of hypertension
• >12 teeth

Exclusion criteria

• >70 years
• smokers (>10 cig/day)
• body mass index>30
• Need of antibioprophylaxis
• Medical treatment including anti-inflammatory drugs and/or antibiotics
• Refractory form of hypertension- aggressive periodontitis

Trial design

76 participants in 1 patient group

blood and cardiological examination

Treatment:

Other: echo Doppler lower limbs