Influence of Perioperative Fluid Management on Intraocular Pressure During Hynecologic Laparoscopic Pelvic Surgery

Ziv Hospital

Status: Unknown

Conditions: Influence of Perioperative Fluid Regime on Intraocular Pressure During Laparoscopic Gynecologic Surgery

Treatments: Other: restrictive fluid regime; Drug: ringer lactate solution

Study type: Interventional

Funder types: Other

Identifiers

NCT01676064

0003-12-ZIV

Details and patient eligibility

About

The aim of this study was to quantify the Intraocular Pressure (IOP) changes in patients undergoing laparoscopic hysterectomy at different time points and body positions throughout the procedure, and to explore the influence of perioperative fluid management on the fluctuations of IOP during perioperative period.

Enrollment: 50 estimated patients

Sex: Female

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 50-60 adult female patients,
• ASA physical status I or II,
• scheduled for elective hynecologic laparoscopic pelvic surgery will be included in the study.

Exclusion criteria

• patients will be excluded if they are > 70 and < 18 yr of age,
• had have a body weight > 150% of their ideal body weight,
• have acute or chronic eye disease,
• receive any medication known to alter IOP, or
• have any mental illnesses.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

liberal fluid group

Active Comparator group

Description:

during surgery 7 ml/kg/hr RL during first intraoperative hr, 5 ml/kg/hr for the subsequent hours.After surgery ( PACU) 1,5 ml/kg/hr;After operation ward on the day of surgery 1,5 ml/kg/hr; Postoperative day 1- 1,5 ml/kg/hr RL, oral fluids;Postoperative day 2-oral fluids and solid food according to surgical allowance.

Treatment:

Drug: ringer lactate solution

restrictive fluid group

Active Comparator group

Description:

during surgery-RL according to "4-2-1" 4 ml/kg/hr for first 10 kg (=40ml/hr) then 2 ml/kg/hr for next 10 kg (=20ml/hr)then 1 ml/kg/hr for any kg over 20 kg of weight. This always gives 60ml/hr for first 20 kg then you add 1 ml/kg/hr for each kg over 20 kg. After surgery (PACU):"4-2-1" rule. After operation ward on the day of surgery 1,5 ml/kg/hr.Postoperative day 1:1,5 ml/kg/hr RL, oral fluids. Postoperative day 2:oral fluids and solid food according to surgical allowance.

Treatment:

Other: restrictive fluid regime