Influence of Positive Margins on Tumour Recurrence and Overall Survival After Gastrectomy for Gastric Cancer

Madrid Health Service

Status: Completed

Conditions: Stomach Neoplasms

Treatments: Other: Observation

Study type: Observational

Funder types: Other

Identifiers

NCT04439812

186/20

Details and patient eligibility

About

Incidence of positive surgical margins after curative gastrectomy ranges from 1% to 20%. It has been suggested that positive surgical margins is an adverse prognosis factor, with a higher local recurrence and worse overall survival (OS). However, the management of these patients remains unclear.

Enrollment: 267 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• all consecutive patients who underwent an oncological gastrectomy due to gastric cancer, between January 2010 and December 2018 at Ramon y Cajal University Hospital.

Exclusion criteria

• distant disease (including patients with positive cytology), early postoperative mortality (within 30 days after surgery) and follow-up data not available. Resections in patients with palliative intent were also excluded.

Trial design

267 participants in 2 patient groups

R=0

Description:

Patients without positive margins after gastrectomy for gastric cancer

Treatment:

Other: Observation

R=1

Description:

Patients with positive margins after gastrectomy for gastric cancer

Treatment:

Other: Observation