Influence of Pregnancy and Post-partum Feeding Method (Breastfeeding Versus Bottlefeeding) on Maternal Hemodynamics (Central and Peripheral) and Vascular Function

Ghent University Hospital (UZ)

Status: Completed

Conditions: Healthy

Treatments: Behavioral: Breastfeeding; Behavioral: Bottlefeeding

Study type: Interventional

Funder types: Other

Identifiers

NCT00699738

2008/297

Details and patient eligibility

About

This study will evaluate the physiological and pathophysiological determinants of pregnancy and feeding method on the maternal cardiovascular system. This includes non-invasive measurements.

Enrollment: 150 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age between 20 and 40 years old
• Singleton pregnancy
• First pregnancy at the minimum age of 18 years
• In good health, especially no cardiovascular diseases, diabetes or a BMI > 30 kg/m2
• Capable in understanding properly the ICF and the investigators

Exclusion criteria

• On chronic medication, especially antihypertensive or antidiabetical drugs
• Multiple pregnancy
• First pregnancy before the age of 18 years old
• Smoking more than 10 cigarettes/day, drinking more than 3 units of alcohol/day or more than 5-6 units of caffeine-containing drinks
• The use of any extralegally drugs
• Not able to have reliable blood pressure or hemodynamic data at screening

Trial design

Primary purpose: Health Services Research

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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150 participants in 3 patient groups

1

Experimental group

Description:

Healthy women during pregnancy and in the postpartum period, breastfeeding

Treatment:

Behavioral: Breastfeeding

2

Active Comparator group

Description:

Healthy women during pregnancy and in the postpartum period,bottlefeeding

Treatment:

Behavioral: Bottlefeeding

3

No Intervention group

Description:

Healthy non-pregnant women