Influence of Rapydan on Clinical Chemistry and Hematology Measurements

LabNoord

Status: Completed

Conditions: Healthy

Treatments: Drug: Rapydan

Study type: Interventional

Funder types: Other

Identifiers

NCT00765934

RapydanClinicalChemistry

Details and patient eligibility

About

There is an increasing awareness of the importance of treating procedure-related pain. Patients undergoing vascular access procedures are often afraid of needles and the discomfort associated with injections. This type of pain and/or fear can be stressful to patients. [1] For prevention of the pain associated with these procedures, the hospital is using Rapydan plasters. Rapydan consists out of two local anesthetics: lidocaine and tetracaïne. Rapydan produces topical anesthesia after an application time of 30 minutes and is used in the Martini Hospital for pain relieve by venipuncture and IV cannulation. The venous blood draining the anaesthetized skin contains a higher blood concentration of the local anesthetics than does venous blood in other parts of the body [2] Although the concentrations of the local anesthetics are low in patients with normal skin, the question is whether the presence of the local anesthetics which Rapydan contains might influence routine measurements in clinical chemistry and hematology.

Enrollment: 25 estimated patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Volunteers 20-60 years who are decision making competent

Exclusion criteria

Patients with local anesthetic allergy Patients using antiarrhythmic drugs Patients using other local anesthetics

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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25 participants in 1 patient group

Rapydan

Other group

Description:

Internal control. Blood from both arms will be drawn. Only one arm of the subject is treated with Rapydan.

Treatment:

Drug: Rapydan