Influence of Sleep Regularity on Circadian Rhythms, Learning, Performance, and Mood

Mass General Brigham

Status: Completed

Conditions: Physiology

Treatments: Other: Sleep/Wake Schedule

Study type: Interventional

Funder types: Other

Identifiers

NCT02839070

R01HL128538

Details and patient eligibility

About

The study is a combination of outpatient and inpatient monitoring. During the 27-day inpatient portion of the study, the individual's sleep-wake schedule will be varied daily. Volunteers will be randomized to a regular or irregular inpatient schedule.

Enrollment: 27 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy
• BMI between 18.5 and 29.5

Exclusion criteria

• medications
• recent night-work, shift-work, or travel across >2 time zones
• use of medications
• pregnant or within 6 months post-partum

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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27 participants in 2 patient groups

Regular Schedule

Experimental group

Description:

Participant will be on a regular sleep/wake schedule

Treatment:

Other: Sleep/Wake Schedule

Irregular Schedule

Experimental group

Description:

Participant will be on an irregular sleep/wake schedule

Treatment:

Other: Sleep/Wake Schedule