ClinicalTrials.Veeva

Menu

Influence of Sodium Bicarbonate on Time-to-exhaustion at Critical Power in Endurance Athletes

University of Zurich (UZH) logo

University of Zurich (UZH)

Status

Completed

Conditions

Performance

Treatments

Dietary Supplement: Placebo
Dietary Supplement: Sodium bicarbonate

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

During endurance exercise in the heavy and severe intensity domains, the rate at which metabolites that have been associated with the fatigue process (e.g. Pi, ADP, H, and extracellular K) accumulate increases. possibly leading to exercise cessation. Sodium bicarbonate, as a nutritional supplement, has gained attention over the past decades, because it might delay of offset fatigue. To date, there is a controversial discussion about which delivery mode (amount and frequency) might be best in optimizing endurance performance. Since the high ion load consequent to multiple ingestions might increase plasma volume, and consequently decrease bicarbonate concentrations, single acute ingestion could be more beneficial. However, in multi-day competitions or tournaments it might be necessary to use the supplement on a daily basis. Here, the investigators aim at investigating the effects of single dose or multiple dose (on five consecutive days) administration of bicarbonate vs. placebo increases endurance performance and acid-base homeostasis in trained male endurance athletes.

Enrollment

12 patients

Sex

Male

Ages

18 to 45 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria: - male

  • no cold or temperature at beginning or during the study
  • between 18 and 45 years of age
  • active in endurance sports (3 to 5 times per week a moderate to hart training)
  • non-smoker
  • no known cardiovascular or orthopedic problems
  • no known limitations of kidney function
  • no bearer of a cardiac pacemaker
  • no medications with direct influence on the measurements. The whole intake of medicaments has to be declared in the health questionnaire by the participant.
  • requirements of the health questionnaire fulfilled

Exclusion criteria: - female

  • male and age under 18 or over 45 years
  • cold or temperature at the beginning or during the study
  • untrained (less than 3 moderate trainings per week)
  • smoker
  • cardiovascular or orthopedic problems
  • limitations of the kidney function
  • bearer of a cardiac pacemaker
  • medication with direct influence on the measurements. The whole intake of medicaments has to be declared in the health questionnaire by the participant.
  • requirements of the health questionnaire not fulfilled

Trial design

12 participants in 2 patient groups, including a placebo group

Sodium bicarbonate
Active Comparator group
Treatment:
Dietary Supplement: Sodium bicarbonate
Placebo
Placebo Comparator group
Treatment:
Dietary Supplement: Placebo

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems