Influence of Sodium Intake in spondyLoarthriTes (SALT)

Centre Hospitalier Universitaire de Besancon

Status: Enrolling

Conditions: Spondyloarthritis, Axial; Arthritis, Psoriatic

Treatments: Other: measurement of salt intake

Study type: Interventional

Funder types: Other

Identifiers

NCT06259890

2023/807

Details and patient eligibility

About

The aim of the SALT study is to analyze the relationship between dietary sodium intake and disease activity in patients with axial spondyloarthritis (radiographic or non-radiographic) or psoriatic arthritis.

Enrollment: 250 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with axial spondyloarthritis (radiographic or non-radiographic) or psoriatic arthritis
• women who have been menopausal for at least 24 months, surgically sterilized, or, for women of childbearing potentiale, use an effective method of contraception (oral contraceptives, contraceptive injections, intrauterine devices, double-barrier method, contraceptive patches)

Exclusion criteria

• patient treated by cyclosporine, diuretics, angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists.
• current treatment with an anti-IL-17A agent (secukinumab or ixekizumab or bimekizumab or brodalumab) or with an anti-IL23 agent (ustekinumab, guselkumab, risankizumab or tildrakizumab) or previous treatment less than 6 months old.
• patients on systemic corticosteroids with corticosteroid therapy > 10 mg prednisone equivalent
• pregnant woman

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

250 participants in 1 patient group

Patients with radiographic/non-radiographic Axial Spondylitis or psoriatic arthritis

Other group

Description:

Patients with radiographic/non-radiographic Axial Spondylitis or psoriatic arthritis managed in the rheumatology departments of the study centres.

Treatment:

Other: measurement of salt intake