Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary Aldosteronism (ISIRA)

Charles University, Czech Republic

Status and phase: Unknown; Phase 4

Conditions: Primary Aldosteronism

Treatments: Drug: Synacthen infusion during adrenal venous sampling

Study type: Interventional

Funder types: Other

Identifiers

NCT02127840

PAAVS1143

Details and patient eligibility

About

The project is aimed to determine the value of synacthen infusion on the results of adrenal venous sampling in patients examined for primary aldosteronism

Full description

We aim to compare the results of adrenal venous sampling performed without and during synacthen infusion.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: Confirmed primary aldosteronism

Exclusion Criteria: Inability to undergo unilateral adrenalectomy

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

---

40 participants in 2 patient groups

Synacthen

Experimental group

Description:

Synacthen infusion during adrenal venous sampling

Treatment:

Drug: Synacthen infusion during adrenal venous sampling

Without Synacthen

No Intervention group

Description:

Adrenal venous sampling without Synacthen