Influence of Tracheostomy on Lung Deposition in Spontaneously Breathing Patient

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Status: Completed

Conditions: Tracheostomized Patients

Treatments: Other: Nebulization through the tracheostomy; Other: Nebulization through the mouth

Study type: Interventional

Funder types: Other

Identifiers

NCT01882595

Nebu Tracheo

Details and patient eligibility

About

To compare lung deposition of amikacin in two settings: spontaneously breathing through a tracheostomy cannula and through the mouth.

Enrollment: 9 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient who were likely to require an elective tracheostomy surgery as part as their head and neck surgery

Exclusion criteria

• Allergy to Aminoglycosides
• Patients who received Aminoglycosides treatment less than one month prior the surgery
• Pectoralis major flap reconstruction
• Latissimus dorsi flap reconstruction

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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9 participants in 2 patient groups

Nebulization through the tracheostomy

Experimental group

Description:

Each subjects received two nebulization sessions. The first session was performed prior the tracheostomy removal (through the tracheostomy) and the second one when the when the tracheostome was totally scared (through the mouth)

Treatment:

Other: Nebulization through the tracheostomy

Nebulization through the mouth

Active Comparator group

Description:

Each subjects received two nebulization sessions. The first session was performed prior the tracheostomy removal (through the tracheostomy) and the second one when the when the tracheostome was totally scared (through the mouth)

Treatment:

Other: Nebulization through the mouth