Influence of Trigger Threshold on Controlled Twitch Mouth Pressure

Guangzhou Institute of Respiratory Disease

Status: Completed

Conditions: Healthy; COPD

Treatments: Procedure: twitch by magstim

Study type: Interventional

Funder types: Other

Identifiers

NCT01891942

GIRD-566 (Registry Identifier)

Details and patient eligibility

About

The inspiratory pressure trigger is essential when assessing the twitch mouth pressure (Tw Pmo) for avoiding glottic closure. However, the difference in inspiratory pressure trigger threshold may influence the values of Tw Pmo. We sought to determine the trigger threshold for healthy subjects and COPD patients.

Enrollment: 30 patients

Sex: Male

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Clinical diagnosis of COPD
2. Stable with no episodes of exacerbation within the previous 2 months
3. Do not currently being treated with oral corticosteroids

Exclusion criteria

1. Not stable within the previous 2 months.
2. Patients with COPD were currently being treated with oral corticosteroids

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

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30 participants in 2 patient groups

COPD patients

Experimental group

Description:

All of the COPD patients included in this study were stable with no episodes of exacerbation within the previous 2 months. Patients with COPD were not currently being treated with oral corticosteroids.

Treatment:

Procedure: twitch by magstim

normal subjects

Experimental group

Description:

Fifteen healthy men with normal lung function

Treatment:

Procedure: twitch by magstim