Influence of Two Different Preloaded Intraocular Lens (IOLs) on Posterior Capsule Opacification

Hospital Hietzing

Status and phase: Completed; Phase 4

Conditions: Cataract

Treatments: Procedure: cataract surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT00673803

preloaded 2008

Details and patient eligibility

About

Studies showed that a sharp posterior optic edge of an intraocular lens (IOL) inhibits migration of lens epithelial cells in between posterior capsule and optic of the IOL and therefore reduces the rate of posterior capsule opacification (PCO). In present time most IOLs implanted have a sharp posterior optic edge. Due to differences in IOL production different IOLs have different rates of PCO.

Progression in cataract surgery technique allow phacoemulsification through micro-incisions. Therefore there is need for IOLs that can be implanted through incisions of about 2.5 mm.

This study investigates the effect of two different hydrophobic acrylic IOLs with a sharp posterior optic edge on the rate of PCO after implantation through a micro-incision. The results will be compared intraindividually.

Full description

prospective, randomized, bilateral study with intraindividual comparison, implantation of a Polylens Y10 IOL in one eye and implantation of a Polylens Y30 in the contralateral eye.

PCO rate will be detected at 1 year and 2 years.

Enrollment: 40 patients

Sex: All

Ages: 55 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• bilateral age-related cataract
• age 55 to 80 years
• expected postoperative visual acuity of at least 0.5

Exclusion criteria

• amblyopia
• corneal scars
• diabetes
• pseudoexfoliation-syndrome
• earlier ocular surgeries or laser treatments
• intraocular tumors

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

A

Other group

Description:

cataract surgery, implantation of a Polylens Y10

Treatment:

Procedure: cataract surgery

B

Other group

Description:

cataract surgery, implantation of a Polylens Y30

Treatment:

Procedure: cataract surgery