Influence of Two Paraffin Wax Chewing Gums of Different Consistency on the Stimulated Saliva Flow Rate

University Hospital Basel

Status: Completed

Conditions: Xerostomia

Treatments: Diagnostic Test: Chewing wax from the Saliva-Check Buffer from GC Europe; Diagnostic Test: Paraffin Pellets from Aurosan GmbH

Study type: Interventional

Funder types: Other

Identifiers

NCT04661761

2020-00470 ex20Filippi5;

Details and patient eligibility

About

The study examines two different chewing gums with regard to consistency and its influence on the result of sialometry

Full description

The examination (sialometry) is performed on healthy volunteers. The volunteers must chew on a paraffin gum for seven minutes. After each minute, the amount of secreted saliva is spat into a designated cup and evaluated. This test is performed with Aurosan chewing gum and later with GC Europe chewing gum.

Enrollment: 81 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy volunteers
• non-smoker
• no medication

Exclusion criteria

• physical or mental illnesses
• smokers
• regular medication intake
• pregnant women
• dementia or persons who are unable to judge or persons with guardianship
• minor test persons

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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81 participants in 1 patient group

stimulated salivary flow rate

Experimental group

Description:

stimulated salivary flow rate determined in a crossover design: first using Paraffin Pellets from Aurosan GmbH; thereafter using Chewing wax from the Saliva-Check Buffer from GC Europe

Treatment:

Diagnostic Test: Chewing wax from the Saliva-Check Buffer from GC Europe

Diagnostic Test: Paraffin Pellets from Aurosan GmbH