Novel INPUT Screening Tool to Improve Illness Understanding in Patients With Metastatic or Incurable Lung Cancer

M.D. Anderson Cancer Center

Status: Enrolling

Conditions: Metastatic Lung Carcinoma; Lung Carcinoma; Stage IV Lung Cancer AJCC v8

Treatments: Other: Questionnaire Administration; Other: Best Practice

Study type: Interventional

Funder types: Other

Identifiers

NCT06743308

NCI-2024-10305 (Other Identifier)

2024-1519

Details and patient eligibility

About

This clinical trial compares the use of a new screening tool designed to evaluate patients' information needs, preferences, and illness understanding to the usual care to improve illness understanding in patients with lung cancer that has spread from where it first started (primary site) to other places in the body (metastatic) or for which no curative treatment is currently available (incurable). Goal concordant care is a model of care that aligns a patient's medical care with their values, preferences, and goals. Often, patients may not fully understand their illness and prognosis, but this information is important so that they can make fully informed decisions regarding their care that are consistent with their values, preferences, and goals. Completing the Information Needs, Preferences, and Understanding Trial (INPUT) screening tool may allow for more frequent and regular discussions regarding disease status and treatment goals, ultimately resulting in improved patient illness understanding and goal concordant care for patients with metastatic or incurable lung cancer.

Full description

Primary Objectives To estimate the within group effect of perception of curability over 3 months in both the systematic screening group and the usual care group among patients with metastatic or incurable lung cancer who present to the thoracic medical oncology clinic at The University of Texas MD Anderson Cancer Center.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Within 3 months of biopsy-confirmed diagnosis of stage IV lung cancer
• Age 18 or over
• English speaking
• Attending a follow-up visit at the thoracic medical oncology clinic
• Plans to receive or actively undergoing cancer-directed systemic treatment at MD Anderson

Exclusion criteria

• Diagnosis of cognitive impairment or dementia requiring a surrogate decision maker

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

Arm I (Standard care)

Active Comparator group

Description:

Patients undergo standard of care oncology follow-up visits.

Treatment:

Other: Questionnaire Administration

Other: Best Practice

Arm II (INPUT screening)

Experimental group

Description:

Patients complete the INPUT screening tool at each of their standard of care follow up visits, with their medical oncology team.

Treatment:

Other: Questionnaire Administration

Other: Best Practice