Infraclavicular Perineural Dexmedetomidine

Çukurova University

Status: Completed

Conditions: The Analgesic Effects

Treatments: Drug: Dexmedetomidine; Drug: Bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02550782

Mengücek gazi

Details and patient eligibility

About

Infraclavicular block is one of the peripheral nerve block used in upper extremity surgery. Adjuvant agents are used in peripheral nerve blocks to increase the duration and block quality. We investigated that the effects of patient-controlled perineural dexmedetomidine application on postoperative analgesia.

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• be undergoing distal upper extremity surgery
• Be between 18-65 years
• to agree to participate in research

Exclusion criteria

• allergy to dexmedetomidine
• AV block or bradycardia
• being serious cardiac - liver - kidney function disorders
• Being coagulopathy
• neuropathy in the upper extremity
• adrenoceptor agonists or antagonists use

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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60 participants in 2 patient groups

perineural bupivacaine

Active Comparator group

Description:

patient-controlled infraclavicular perineural bupivacaine (1% bupivacaine (marcaine), 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)

Treatment:

Drug: Bupivacaine

Drug: Dexmedetomidine

perineural dexmedetomidine

Experimental group

Description:

patient-controlled infraclavicular perineural dexmedetomidine (1% bupivacaine + 200 mic / 100cc dexmedetomidine, 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)

Treatment:

Drug: Bupivacaine

Drug: Dexmedetomidine