Infusion Laboratory: Protocol 2 (Lisuride) - 3

National Institutes of Health (NIH)

Status and phase: Unknown; Phase 1

Conditions: Cocaine-Related Disorders

Treatments: Drug: Lisuride

Study type: Interventional

Funder types: NIH

Identifiers

NCT00000338

NIDA-3-0010-3

Y01-3-0010-3

Details and patient eligibility

About

The purpose of this study is to evaluate clinical safety issues pertaining to lisuride, to cocaine, and to its interaction in a chronic, crack dependent population, and to determine how pretreatment with lisuride modifies the subjective as well as physiological effects of cocaine.

Sex: All

Ages: 21 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

M/F ages 21-50. Meet DSM-IV criteria for cocaine dependence. Agree to conditions of the study and sign informed consent.

Exclusion criteria

Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nuring women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical condtions that deem participation to be unsafe.