Infusion Laboratory: Protocol 3 (Risperidone) - 4

National Institutes of Health (NIH)

Status and phase: Unknown; Phase 1

Conditions: Cocaine-Related Disorders

Treatments: Drug: Risperidone

Study type: Interventional

Funder types: NIH

Identifiers

NCT00000339

NIDA-3-0010-4

Y01-3-0010-4

Details and patient eligibility

About

The purpose of this study is to evaluate clinical safety issues pertaining to risperidone, to cocaine and to its interaction, and to determine how pretreatment with risperidone modifies the subjective as well as physiological effects of cocaine.

Sex: All

Ages: 21 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

M/F ages 21-50. Meet DSM-IV criteria for cocaine dependence. Agree to conditions of the study and sign informed consent.

Exclusion criteria

Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nuring women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical condtions that deem participation to be unsafe.