Infusion Treatments of Chronic Peripheral Neuropathic Pain

Hacettepe University

Status: Completed

Conditions: Neuropathic Pain

Treatments: Drug: Lidocain; Drug: Ketamine

Study type: Observational

Funder types: Other

Identifiers

NCT06297915

2022/08-45

Details and patient eligibility

About

This study aimed to evaluate and compare the efficacy of ketamine and lidocaine infusion in patients with chronic peripheral neuropathic pain.

Patients who received intravenous ketamine infusion and the other patient group who received intravenous lidocaine infusion were evaluated in the study. Pain scores and quality of life were assessed with scales before treatment at two weeks, two months, and six months after treatment.

Full description

This study, it was aimed to evaluate and compare the efficacy of intravenous infusion of ketamine and lidocaine, which have been known and used in pain management and which have recently increased interest in the treatment of peripheric neuropathic pain.

Enrollment: 102 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18-65 years of age
• Patients with peripheral neuropathic pain (radicular neuropathy, diabetic neuropathy, complex regional pain syndrome type 2, traumatic peripheral nerve injury, trigeminal neuralgia, postherpetic neuralgia)
• Patients who was evaluated by DN4 scores with of ≥4 points

Exclusion criteria

• Patients with central nervous system disease .
• Patients with cancer related neuropatic pain.
• Patients with central neuropathic pain patterns.
• Patients with renal, hepatic, cardiovascular, and psychiatric diseases.
• Patients whose treatment could not be completed due to side effects or other reasons.
• Patients who had lost their follow-up .