Inguinal Hernia and Arterial Disease (HEARD)

University of Catanzaro

Status: Unknown

Conditions: Arterial Disease; Inguinal Hernia

Treatments: Diagnostic Test: Echo duplex scan of arterial system; Diagnostic Test: In-office vascular visit

Study type: Observational

Funder types: Other

Identifiers

NCT04428138

ER.ALL.2018.30

Details and patient eligibility

About

Inguinal hernias are associated with problems related to the venous system by the linking to extracellular matrix alterations (ECM). On the other hand, arterial diseases (arterial aneurysms, carotid, stenosis, peripheral artery disease) are widespread in the general population and may share others pathological pathways related to ECM impairment. Aim to this study is to evaluate the prevalence of arterial diseases in patients with inguinal hernia.

Full description

Previous studies showed the correlation between inguinal hernias and venous disease. The common pathophysiological pathway between these clinical conditions is linked to extracellular matrix (ECM) alterations. Arterial diseases, mainly represented by carotid stenosis, peripheral artery disease and arterial aneurysms, are widespread in western population and are responsible of high rates of morbidity and mortality. These diseases are also related to some ECM alterations.

Aim of this cross-sectional study is to evaluate the prevalence of arterial disease among patients with inguinal hernias. The primary endpoint of this study is to provide new epidemiological evidences on this association that may help physicians in novel preventive strategies. The study will consider the inclusion of consecutive patients assessed for inguinal hernia over 1 year period in order to study the prevalence of concomitant arterial disease, by means of office visit, echo duplex scan of the aorta and its main branches, carotid arteries and lower limb arteries.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with inguinal hernia

Exclusion criteria

• patients with malignancies

Trial design

100 participants in 1 patient group

Patients with Inguinal hernia

Description:

Patients presenting with inguinal hernia will undergo vascular in-office visit and echo duplex of aorta, carotid arteries and lower limb arteries in order to detect any abnormalities related to arterial disease (aneurysm, stenosis, flow alteration).

Treatment:

Diagnostic Test: Echo duplex scan of arterial system

Diagnostic Test: In-office vascular visit