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Inhalation Intervention for Nausea in the Emergency Department

Brooke Army Medical Center logo

Brooke Army Medical Center

Status

Completed

Conditions

Vomiting
Nausea

Treatments

Other: Alcohol prep pad group
Other: Normal Saline prep pad

Study type

Interventional

Funder types

Other U.S. Federal agency

Identifiers

NCT02092441
BAMC 395266-1

Details and patient eligibility

About

Randomized controlled trial comparing inhalation of isopropyl alcohol vs placebo (normal saline) pads to treat nausea in emergency department patients.

Full description

This study is to investigate if inhaling the scent of a typical medical alcohol prep pad will alleviate nausea as compared to a identically packaged normal saline prep pad for the Emergency Department patient with nausea. The study length will be 10 minutes long. The subjects will take several deep nasal inhalations at the 0, 2, 5 minute marks. Level of nausea will be recorded during these times and at 10 minutes. The investigators will also assess satisfaction of the intervention. As in previous post operative unit studies,the hypothesis is that there will a significant difference in levels of nausea between the alcohol pad group versus the normal saline pad group.

Enrollment

80 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • age range of 18-65 years of age
  • complaint of nausea and or vomiting
  • ability to breathe through nose
  • ability to read and write English

Exclusion criteria

  • allergy to isopropyl alcohol
  • pregnancy or pregnancy status unknown to subject. Pregnancy test only if part of clinical course.
  • recent upper respiratory infection
  • recent intake of cefoperazone, disulfiram, or metronidazole or any other medications that are known produce nausea when exposed to alcohol.
  • use of antiemetic or psychoactive drug within 24 hours
  • alcohol abuse
  • nicotine within last 4 hrs

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

80 participants in 2 patient groups, including a placebo group

Alcohol prep pad group
Active Comparator group
Description:
isopropyl alcohol prep pad
Treatment:
Other: Alcohol prep pad group
Normal Saline prep pad
Placebo Comparator group
Description:
normal saline prep pad
Treatment:
Other: Normal Saline prep pad

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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