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Inhaled Sevofluran vs Endovenous Propofol for Colonoscopy

C

Centro Medico Docente la Trinidad

Status

Completed

Conditions

Anesthesia

Treatments

Drug: Sevoflurane
Drug: Propofol

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

To compare the anesthetic efficacy of the inhalation versus intravenous technique for maintenance of sedation in patients undergoing endoscopy.

A longitudinal, randomized clinical study of 32 patients of both sexes ASA I-III, aged 18-80 years undergoing diagnostic colonoscopy, which was randomly divided into 2 groups. In both, intravenous induction with propofol (2-2.5 mg / kg) was performed, Group A remained sedated with propofol infusion (1-2 mg / kg / min); Group B by inhalation with sevoflurane at a concentration of 2 vol% through a nasal cannula with an oxygen flow.

Enrollment

32 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age between 18 and 80 years
  • physical status I, II and III according to the criteria of the American Society of Anesthesiology (ASA)
  • patients who are going to undergo diagnostic colonoscopies
  • patients who signed the informed consent

Exclusion criteria

  • Allergy or hypersensitivity to some of the reference drugs in the study
  • patients with proven liver disease
  • suspicion or confirmation of pregnancy
  • antecedent or risk of malignant hyperthermia
  • fasting less than 8 hours
  • patients with psychic disorders or mental incapacity that make it difficult to understand their participation in the study
  • patients who have acute illnesses that compromise their health for which the study cannot be performed

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

32 participants in 2 patient groups

Group Propofol
Experimental group
Description:
propofol infusion
Treatment:
Drug: Propofol
Group Sevoflurane
Experimental group
Description:
inhalation with sevoflurane
Treatment:
Drug: Sevoflurane

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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