Injection of Corticoids for the Treatment of Acute Sprains of the Proximal Interphalangeal Joints of the Fingers.

CHU Brugmann University Hospital

Status and phase: Completed; Phase 2

Conditions: Sprain

Treatments: Drug: Diprophos

Study type: Interventional

Funder types: Other

Identifiers

NCT02916940

CHUB-Diprophos-IPP

Details and patient eligibility

About

There is currently no real consensus on the optimal management of acute sprains of the proximal interphalangeal joint of the long fingers.

The aim of this study is to assess the beneficial effect of an injection of corticosteroids for the treatment of this type of sprain (one single sub-cutaneous injection, in the acute phase). This treatment, if effective, might become the treatment of choice for these types of injuries, instead of a prolonged immobilization or a careful early mobilization.

Enrollment: 60 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults over 18 years old
• Type I and II and III of the Eaton classification (except if fracture/luxation with more than 50% of the articular surface injured)
• Trauma of one articulation only
• Consultation within 2 weeks of trauma

Exclusion criteria

• Patients under 18 years old and over 80 years old
• Pregnant/nursing women
• Eaton classification Type II with a fracture affecting more than 50% of the articular surface, or persistant instability after reduction.
• Open wounds, nerve lesion with sensitive issue and any wound needing a surgical intervention
• Underlying pathologies: rhumatological, neurological, congenital (giving hyperextensive articulations as a result)
• Corticoids allergy
• Infection within the treated zone
• Trauma antecedents at the level of the tendons.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Diprophos

Experimental group

Description:

Patients having had a sprain of the long fingers, within 2 weeks of consultation. This group will receive a single injection of corticoids.

Treatment:

Drug: Diprophos

Control group

No Intervention group

Description:

Patients having had a sprain of the long fingers (Eaton classification type I and II), within 2 weeks of consultation. This group will receive the standard of care treatment, without injection of corticoids.