Injection of Hormone to Enhance Implantation in Embryo Transfer After IVF

Servy Massey Fertility Insititute

Status: Completed

Conditions: Infertility

Treatments: Drug: HCG is introduced

Study type: Interventional

Funder types: Other

Identifiers

NCT01986374

HCG 2013

Details and patient eligibility

About

The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.

Full description

The study is in pilot phase, uncontrolled. The risks appear to be minimal and there are conflicting new reports being announced.

A small amount of fluid with HCG is injected into the uterus. HCG is a potent signal to the uterus for preparation for implantation.

This is not a funded study. Three published studies suggest the approach is valid; one refutes the concept.

Enrollment: 75 patients

Sex: Female

Ages: 21 to 47 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• infertility patients undergoing IVF with good expectation of two embryos day 3 or day 5. must speak and read English. Includes donor eggs.

Exclusion Criteria:abnormal uterus

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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75 participants in 1 patient group

HCG is introduced with small catheter.

Experimental group

Description:

phase 1 non randomized pilot

Treatment:

Drug: HCG is introduced