Injection of Hyaluronic Acid Versus Corticosteroid for Treatment of Trigger Finger

Dubai Health Authority

Status and phase: Unknown; Early Phase 1

Conditions: Trigger Finger

Treatments: Drug: hyaluronic acid (20 mg/2 mL); Drug: Triamcinolone acetonide 10mg/ml

Study type: Interventional

Funder types: Other

Identifiers

NCT04645303

DSREC-12/2019_03

Details and patient eligibility

About

The aim of the study is to compare the therapeutic effects of hyaluronic acid versus steroid injections in treating trigger fingers using ultrasound guidance

Full description

A prospective randomized controlled study designed to compare the outcomes of injecting patients with trigger finger with hyaluronic acid versus corticosteroid under ultrasound guidance

Enrollment: 100 estimated patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult (>18 years)
• Patients with a clinical diagnosis of trigger finger grade 1-3 on the Quinnell grading scale and confirmed diagnosis by ultrasound.

Exclusion criteria

• Quinnell's classification grade IV (contracture)
• Prior injection within 6 months
• Prior operation of the affected finger
• Presence of any contracture in the proximal interphalangeal or metacarpophalangeal joint, and
• History of diabetes, hypothyroidism, and
• Rheumatic or connective tissue disease
• Allergy to triamcinolone or hyaluronic acid
• Pregnancy
• Secondary triggering e.g. Trauma, infection
• Trigger finger symptoms duration >6 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

Hyaluronic acid

Experimental group

Description:

1mL of hyaluronic acid (20 mg/2 mL; Hyalgan, Fidia, Abano Terme, Italy) infiltration at A1-Pulley under ultrasound guidance after subcutaneous 2% lidocaine without epinephrine infiltration of the skin overlying the A1-pulley.

Treatment:

Drug: hyaluronic acid (20 mg/2 mL)

Triamcinolone acetonide

Active Comparator group

Description:

1 mL of Triamcinolone acetonide 10mg/ml infiltration at A1-Pulley under ultrasound guidance after subcutaneous 2% lidocaine without epinephrine infiltration of the skin overlying the A1 pulley.

Treatment:

Drug: Triamcinolone acetonide 10mg/ml