Innate Immunity in Allergic Asthma

University of Central Florida

Status: Enrolling

Conditions: Asthma

Study type: Observational

Funder types: Other

Identifiers

NCT06068335

CR00001150

Details and patient eligibility

About

The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants must be at least 18 years of age
• no history of allergic disease (healthy controls), have clinically diagnosed allergies, or have clinically diagnosed asthma.

Exclusion criteria

• Pregnant women and prisoners will be excluded from the study.
• Individuals currently suffering from any acute infections and those known to suffer from light-headedness will be excluded.