Innovations in Dementia Empowerment and Action (IDEA)

University of Washington

Status: Completed

Conditions: Alzheimer Disease; Mild Cognitive Impairment; Lewy Body Dementia; Vascular Dementia; Parkinson Disease Dementia; Dementia

Treatments: Behavioral: Reducing Disabilities in Alzheimer's Disease (RDAD); Behavioral: Innovations in Dementia Empowerment and Action (IDEA)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT03550131

STUDY00003076

1R01AG055488-01A1 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The lack of efficacious research-based interventions for such vulnerable older adults with Alzheimer's disease and related dementias (AD/RD) and their caregivers (CGs) is a significant public health problem. Caregiving of sexual/gender minority older adults with AD/RD is of concern due to social stigma, marginalization, and isolation, which may be barriers to sustaining caregiving. It is necessary and timely to translate evidence-based culturally adaptable interventions for this underserved and stigmatized population. Reducing Disability in Alzheimer's Disease (RDAD) has been evaluated in a randomized controlled trial and has shown to successfully train community-dwelling CR (care receiver)-CG dyads to increase the physical activity and functioning of individuals with AD/RD and their CGs and to teach CGs techniques for managing behavioral symptoms of CRs. RDAD consequently decreases stress of CGs, delays institutionalization of CRs, and increases health related quality of life (HRQOL) of CRs and CGs. Thus, this study will evaluate the effect of the standard RDAD among lesbian, gay, bisexual, and transgender (LGBT) CRs with AD/RD and their CGs, and this study will test a personalized intervention tailored to better respond to distinct risks experienced by CGs and LGBT CRs with AD/RD, addressing unique sexual/gender minority CG risk factors (e.g., identity management, stigma-related adverse or traumatic life events, and lack of social support).

Full description

We will address the following aims:

Aim 1. Test the translation and enhancement of intervention designed to increase physical activities of older adult care receivers (CRs) with AD/RD and their CGs. Aim 2. Evaluate the short- and long-term effect of the standard and personalized intervention on primary (physical activity and functioning; perceived stress for CGs; independence/residential status (institutionalization) for CRs) and secondary outcomes (HRQOL; depressive symptomatology; behavioral disturbances for CRs). Aim 3. Test the moderating roles of CR-CG characteristics, including type of CR-CG relationship, sex, and severity of CR AD/RD, on the treatment effect of the standard and personalized intervention.

Enrollment: 322 patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria for care receiver

• Age at enrollment is 50 years of age or older
• Have dementia, (e.g., Alzheimer's disease, mild cognitive impairment, Vascular dementia, Parkinson's disease, Lewy Body dementia) or memory loss significant enough to affect daily activities
• Living in the community, not in a care facility.
• Living in the U.S.
• Either the care receiver or care giver must self-identify as LGBT (or sexual or gender non-binary or same sex sexual behavior)

Inclusion criteria for care giver

• Provide care to the care recipient with dementia.
• Willing to spend 30 minutes daily for study activities (or coordinate for someone to.)
• Unpaid
• Live in the community, not in a care facility
• Living in the U.S.

Neither care receiver nor caregiver:

• Has known terminal illness (with death anticipated within the next 12 months)
• Was hospitalized for a psychiatric disorder in the 12 months prior to baseline
• Is currently suicidal or having major hallucinations or delusions
• Plans to move to long term care setting within 6 months of enrollment.
• Has any physical limitations/chronic conditions preventing participation in an exercise program.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

322 participants in 2 patient groups

Standard intervention

Active Comparator group

Description:

Reducing Disabilities in Alzheimer's Disease (RDAD): 9 60-minute virtual sessions for 6 weeks and 4 15-minute follow-up phone sessions for 4 months

Treatment:

Behavioral: Reducing Disabilities in Alzheimer's Disease (RDAD)

Personalized intervention

Experimental group

Description:

Innovations in Dementia Empowerment and Action (IDEA): 9 60-minute virtual sessions for 6 weeks and 4 15-minute follow-up phone sessions for 4 months

Treatment:

Behavioral: Innovations in Dementia Empowerment and Action (IDEA)