Inotropic Treatment With Levosimendan (SimdaxR)in Heart Surgery

Ullevaal University Hospital

Status: Terminated

Conditions: Cardiac Surgery; Heart Failure

Treatments: Drug: levosimendan

Study type: Interventional

Funder types: Other

Identifiers

NCT01221116

INSI-study

Details and patient eligibility

About

Hypothesis: Treatment with levosimendan will preserve myocardial function and hemodynamics after cardiac surgery and lead to reduced stay at intensive care unit

Full description

Single center, prospective, randomized parallel-group, double-blinded study

Enrollment: 23 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• EF (ejection fraction)<40%

Exclusion criteria

• renal failure, liver failure

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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23 participants in 1 patient group

1: Type of surgery

No Intervention group

Description:

Two types of patients are compared (placebo vs levosimendan): CABG - coronary artery bypass grafting and AVR - aortic valve replacement (either with or without CABG - coronary artery bypass grafting)

Treatment:

Drug: levosimendan