Inspection of the Colon Using a Retrograde Viewing Device for Detection of Colorectal Polyps

University of Erlangen-Nürnberg Medical School

Status: Unknown

Conditions: Polyps; Adenoma

Treatments: Diagnostic Test: Retroviewing endoscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT04107376

Ludwig Demling Endoscopy

Details and patient eligibility

About

During standard colonoscopy a substantial number of colorectal polyps may be missed. Previous studies have found a 12-28% of miss rate for all polyps, a 31% for hyperplastic polyps and 6-27% for adenomas. In this study it is tested whether a retro viewing endoscope can detect more colorectal polyps in comparisson to standard forward viewing endoscopy. Further, ppolyps detected, mean adenomas per Patient and withdrawal time are recorded.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• screening colonoscopy
• 18 years of age

Exclusion criteria

• inflammatory bowel disease
• inadequate bowel preparation

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

Retroviewing endoscopy (RVE)

Experimental group

Description:

Withdrawal in every colonic segment with SFV (standard forward view) followed by another withdrawal with the retroviewing endoscope. Allocation of patients to each arm (RVE or SFVE) is done by randomization using sealed envelopes.

Treatment:

Diagnostic Test: Retroviewing endoscopy

standard forward viewing endoscopy (SFVE)

Active Comparator group

Description:

Withdrawal in every colonic segment with SFV followed by another withdrawal with SFV. Allocation of patients to each arm (RVE or SFVE) is done by randomization using sealed envelopes.

Treatment:

Diagnostic Test: Retroviewing endoscopy