Inspiratory Muscle Training in Sarcoidosis

Gazi University

Status: Completed

Conditions: Sarcoidosis

Treatments: Device: Sham inspiratory muscle training; Device: Inspiratory muscle training

Study type: Interventional

Funder types: Other

Identifiers

NCT02270333

GaziU

Details and patient eligibility

About

Respiratory muscle weakness results with decreased exercise capacity, worse fatigue, dyspnea and quality of life in patients with sarcoidosis. However, no study investigated the effects of inspiratory muscle training (IMT), therefore effects of IMT on outcomes in patients with sarcoidosis were investigated.

Full description

Patients were diagnosed with sarcoidosis according to the criteria of the latest American Thoracic Society (ATS)/European Respiratory Society (ERS)/World Association of Sarcoidosis and Other Granulomatous (WASOG) Disorders statement on sarcoidosis. Primary outcome measurement was respiratory muscle strength, secondary outcomes were, exercise capacity quality of life, fatigue and depression.

Enrollment: 30 patients

Sex: All

Ages: 20 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinically stable
• Under standard medication
• Stage I and IV
• No change in medications over three months

Exclusion criteria

• Cognitive disorders
• Current corticosteroid use
• Having co-morbidity to prevent performing IMT
• Acute infection
• Orthopedic and neurological problems

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 2 patient groups

Treatment group

Active Comparator group

Description:

Intervention: Treatment group received inspiratory muscle training (IMT) using POWERbreathe Classic threshold loading device .

Treatment:

Device: Inspiratory muscle training

Control group

Sham Comparator group

Description:

Sham: Control group received sham inspiratory muscle training using POWERbreathe Classic threshold loading device .

Treatment:

Device: Sham inspiratory muscle training