Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow

US Department of Veterans Affairs (VA)

Status: Completed

Conditions: Hypertension

Study type: Observational

Funder types: Other U.S. Federal agency

Identifiers

NCT00018304

AGCG-005-98S

Details and patient eligibility

About

The overall objective of this proposal is to examine the contribution of changes in total body fat, enhancement in insulin-mediated vasodilatation and enhancement in endothelium-derived nitric oxide production to the improvements in metabolic insulin action. In addition, the study will track whether these improvements are related to changes in blood pressure.

Sex: All

Ages: 50 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Age 50 - 75 years, elevated blood pressure, BMI greater than 25 but less than 40 kg/m2