Insulin- and Glucose Metabolism in Pulmonary Arterial Hypertension

Medical University of Graz

Status: Completed

Conditions: Insulin Resistance

Study type: Observational

Funder types: Other

Identifiers

NCT03584607

29-066 ex 16/17

Details and patient eligibility

About

Insulin resistance is a key mechanism in metabolic disorders, which has also been implicated in the development of pulmonary hypertension. In this pilot study, the investigators´ goal is to directly determine insulin sensitivity in idiopathic pulmonary arterial hypertension patients and to compare the results with data from healthy controls.

Enrollment: 10 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• signed informed consent form
• patients with idiopathic or hereditary pulmonary hypertension / healthy controls

Exclusion criteria

• premenopausal women
• other relevant lung disease
• relevant left heart disease
• untreated systemic hypertension
• Diabetes mellitus
• pulmonary hypertension other than idiopathic or hereditary form

Trial design

10 participants in 2 patient groups

Idiopathic Pulmonary Arterial Hypertension patients

Description:

Blood sampling Insulin resistance-measurement

Healthy controls

Description:

Blood sampling Insulin resistance-measurement