Insulin and Standard Management in Hypertriglyceridemic Acute Pancreatitis

University Medical Centre Ljubljana

Status and phase: Not yet enrolling; Phase 4

Conditions: Hypertriglyceridemia; Acute Pancreatitis

Treatments: Other: standard treatment; Biological: insulin

Study type: Interventional

Funder types: Other

Identifiers

NCT05487833

InzulinHTGAP

Details and patient eligibility

About

To compare the efficacy of infusion containing insulin and infusion without insulin on reduction of triglycerides in acute hypertriglyceridemic pancreatitis

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• acute pancreatitis
• triglycerides > 15 mmol/l

Exclusion criteria

• diabetes on peroral therapy or insulin
• blood glucose > 11 mmol/l
• pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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30 participants in 2 patient groups, including a placebo group

insulin

Experimental group

Treatment:

Biological: insulin

standard management

Placebo Comparator group

Treatment:

Other: standard treatment