Insulin Dose Calculation Software in Insulin Therapy (IDCST)

xiaolong zhao

Status: Enrolling

Conditions: Artificial Intelligence; Time in Range; Insulin Therapy

Treatments: Device: Wechat program

Study type: Interventional

Funder types: Other

Identifiers

NCT05389839

21Y11904700

Details and patient eligibility

About

Insulin therapy is the mainstream glucose-lowering program for hospital glucose management. Intelligent insulin dose calculation software based on fingertip glucose monitoring is born in response to the situation. A new generation of continuous blood glucose monitoring technology compared with traditional monitoring technology provides more abundant blood sugar change information.The development of the continuous glucose monitoring technology espcially in blood sugar change trend arrow information, the intelligent insulin dose adjustment sequence based on WeChat program is developed. We plan to carry out a randomized controlled study on patients receiving insulin therapy, in which the insulin dose is adjusted according to the information of four blood glucose monitoring points (before meals and before bed), and randomly divided into two groups, one group is adjusted according to the experience of clinicians, the other group is adjusted according to Wechat program, and glucose monitoring is continued for 1 week. bBood glucose control index of TIR , and the incidence of hypoglycemia and hyperglycemia, hospitalization days and cost was observed. This study ihas great clinical value.

Full description

The problems related to blood glucose in non-endocrine departments are becoming more and more serious.Glucose control level is closely related to the prognosis and cost of inpatients. Insulin therapy is the mainstream glucose-lowering program for hospital glucose management. Intelligent insulin dose calculation software based on fingertip glucose monitoring is born in response to the situation. A new generation of continuous blood glucose monitoring technology compared with traditional monitoring technology provides more abundant blood sugar change information.The development of the continuous glucose monitoring technology espcially in blood sugar change trend arrow information, the intelligent insulin dose adjustment sequence based on WeChat program is developed. We plan to carry out a randomized controlled study on patients receiving insulin therapy, in which the insulin dose is adjusted according to the information of four blood glucose monitoring points (before meals and before bed), and randomly divided into two groups, one group is adjusted according to the experience of clinicians, the other group is adjusted according to Wechat program, and glucose monitoring is continued for 1 week. bBood glucose control index of TIR , and the incidence of hypoglycemia and hyperglycemia, hospitalization days and cost was observed. This study ihas great clinical value.

Enrollment: 182 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Non-endocrine departments;
• 2. Age 18-70;
• 3. Currently using intensive insulin therapy with basic meals;
• 4. Belong to type 1 or Type 2 diabetes
• 5. Hospitalized patients 6. Regular meals

Exclusion criteria

• 1. Unwilling to participate or unable to cooperate.
• 2. Myocardial infarction or cardiovascular and cerebrovascular events in the last 3 months;
• 3. Glomerular filtration rate < 45 ml/min / 1.73 m2;
• 4. Other serious concomitant diseases;
• 5. Liver function transaminase is 2 times higher than the upper limit of normal range;
• 6. Use of oral hypoglycemic drugs other than metformin
• 7. Asymptomatic hypoglycemia

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

182 participants in 2 patient groups

Wechat program guidance group

Experimental group

Description:

Wechat program guidance group using insulin dose calculator

Treatment:

Device: Wechat program

clinical experience treatment group

Active Comparator group

Description:

clinical experience treatment group using physician experience

Treatment:

Device: Wechat program