Insulin Pre-treatment for Steroid-associated Hyperglycemia in Pregnant Diabetic Patients

University of Minnesota (UMN)

Status and phase: Withdrawn; Phase 4

Conditions: Hyperglycemia in Pregnant Diabetic Patients

Treatments: Drug: insulin pre-treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT01875107

1301M26861

Details and patient eligibility

About

Our objective is to assess whether pre-treatment with a fixed dose of insulin, based on weight, given to pregnant patients with gestational or preexisting diabetes receiving betamethasone can provide adequate glycemic control.

Our hypothesis is that pre-treatment with a weight-based calculated insulin dose will help maintain euglycemia for pregnant patients with gestational and preexisting diabetes after steroid administration, and possibly impact length of hospital admission.

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Pregnant women with gestational or pre-existing diabetes admitted to the University of Minnesota
2. Must be 18 years or older
3. Must speak English, Spanish, or Somali
4. Patients must receive steroids for fetal lung maturity as part of their hospital course

Exclusion criteria

1. Pregnant women with Type 1 Diabetes, or Type 2 diabetes with evidence of end-organ disease
2. Pregnant women who need to be emergently delivered due to maternal or fetal complications of pregnancy

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

insulin pre-treatment

Experimental group

Description:

insulin pre-treatment of pregnant diabetic patients who receive betamethasone

Treatment:

Drug: insulin pre-treatment