Insulin Pump vs Multiple Daily Injection on Cardiovascular Outcomes (ITALICO)

University of Pavia

Status: Completed

Conditions: Diabetes Mellitus

Treatments: Device: CSII

Study type: Observational

Funder types: Other

Identifiers

NCT03338439

20170003557

Details and patient eligibility

About

The aim of this study was to evaluate if the positive effects recorded on glycemic control with CSII were maintained on the long term compared to multi-daily injections (MDI). The secondary objective was to evaluate if there is a reduction of type and number of cardiovascular events (CV) in CSII group compared to MDI group after 8 years of observation. This retrospective, observational trial evaluated 104 diabetic patients with prior treatment with MDI initiating CSII therapy compared to 109 diabetic patients continuing MDI.

Enrollment: 215 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with type 1 or 2 diabetes with prior treatment with MDI initiating CSII therapy with tubed insulin pumps
• patients type 1 or 2 diabetes with prior treatment with MDI continuing MDI
• patients attending the center for at least 8 years

Exclusion criteria

• patients not taking insulin

Trial design

215 participants in 2 patient groups

CSII

Description:

CSII: patients with continuous subcutaneous insulin infusion

Treatment:

Device: CSII

MDI

Description:

MDI: patients with multi-daily injections