Insulin Sensitivity of the Brain in Pathogenesis of Diabetes Mellitus Type 2

University Hospital Tuebingen

Status: Unknown

Conditions: Human Physiology of Energy Homeostasis

Treatments: Drug: Saline; Drug: Human insulin

Study type: Interventional

Funder types: Other

Identifiers

NCT00638209

MEG-KFO-2

KFO-114

EudraCT 2006-004734-32

Details and patient eligibility

About

The purpose of the study is to investigate whether insulin sensitivity of the human brain correlates with insulin sensitivity of the liver.

Enrollment: 42 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18-70 Risk factor(s) for type 2 diabetes (e.g. overweight, family history of diabetes)

Exclusion criteria

• Type 2 diabetes pregnancy acute or chronic diseases

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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42 participants in 2 patient groups, including a placebo group

I

Active Comparator group

Treatment:

Drug: Human insulin

P

Placebo Comparator group

Treatment:

Drug: Saline