Insulin Variance Throughout the Day
Status
Conditions
Details and patient eligibility
About
This study is designed to determine whether the sensitivity of a participant's insulin varies from the morning to the evening.
Full description
Study visit 1: about 16 hours - The participant will arrive to the visit fasting.
The participant will have an oral glucose tolerance test which takes about 3 ½ hours.
An IV line will be placed in the participant's arm vein for blood draw purposes and will remain there throughout the testing. A blood sample will be drawn 15 minutes and just before the participant will drink a sugar solution consisting of 75 grams of glucose. Blood will be drawn at specific times after the participant consumes the drink.
The participant will have a second oral glucose tolerance test which takes about 3 ½ hours. An IV line will be placed in the participant's arm vein for blood draw purposes and will remain there throughout the testing. A blood sample will be drawn 15 minutes and just before the participant drinks a sugar solution. Blood will be drawn at specific times after the participant consumes the drink.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Are a healthy male or female
- Have a fasting blood sugar that is between normal and diabetes.
- Are between 18 and 70 years of age, inclusive.
Exclusion criteria
- Are pregnant or breast-feeding a child
- Take a medication for diabetes
- Take a medication like cortisone that can change your blood sugar.
- Take a medication chronically that has not been at a stable dose for at least 1 month
- Take medication for psychosis that is known to change timing in the day - night cycle
Trial design
11 participants in 1 patient group
Trial contacts and locations
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Central trial contact
Tance Sonnier, BS; Jeffrey Gimble, MD, PhD
Data sourced from clinicaltrials.gov
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