Integrated Coronary Multicenter Imaging Registry

Yonsei University

Status: Unknown

Conditions: Coronary Artery Disease

Treatments: Other: FFR; Other: OCT (Optical Coherence Tomography); Other: Coronary CTA

Study type: Observational

Funder types: Other

Identifiers

NCT03298282

1-2017-0049

Details and patient eligibility

About

The coronary images of selective angiography and optical coherence tomography with FFR(Fractional Flow Reserve) values of the intermediate lesions (40-70% stenosis) will be prospectively registered.

Full description

The patients with intermediate lesions after CT angiography and invasive coronary angiography will be screened, and optical coherence tomography, FFR and selective CT angiography will be performed. The coronary images and FFR values will be registered, and the patients will be followed-up up to 2 years to investigate the adverse clinical events.

Enrollment: 180 estimated patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who underwent coronary CT angiography because of chest pain
• Patients who need OCT or FFR evaluation because of intermediate lesions according to invasive angiography (diameter stenosis of 40-70%)
• Age: 20-80 yrs
• Patients who consent and fully understand the protocol
• Patients who consent the clinical follow-up
• Patients who can be followed-up

Exclusion criteria

• Patients who had contrast allergy
• Patients who had unstable blood pressure needing the vasopressors
• Patients who had severe left ventricular function (left ventricular ejection fraction<30%)
• Chronic kidney disease who had Cr level of greater than 2.0 mg/dl
• Patients whose expected survival is less than 12 months
• Patients who had a severe valvular disease

Trial design

180 participants in 1 patient group

Imaging Registry

Description:

Imaging cohort: Patients with intermediate lesions

Treatment:

Other: OCT (Optical Coherence Tomography)

Other: FFR

Other: Coronary CTA