Integrated Diagnosis and Treatment of CKD on Outcomes

Capital Medical University

Status: Enrolling

Conditions: Anemia; Hypertension; Chronic Kidney Diseases; Malnutrition; Hyperlipidemias; Hyperglycemia; Chronic Kidney Disease-Mineral and Bone Disorder

Treatments: Other: Integrated diagnosis and treatment for CKD

Study type: Observational

Funder types: Other

Identifiers

NCT05242055

202112-11

Details and patient eligibility

About

Objective: To establish a study cohort and follow up of patients with CKD in our hospital, and evaluate the status of integrated CKD diagnosis and treatment according to guidelines in the real world, as well as the clinical prognosis of patients with different stratification.

Methods: By establishing a cohort of 1000 patients with CKD and conducting long-term follow-up, integrated diagnosis and treatment for CKD was performed, namely: Regular monitoring, control of blood pressure, blood glucose, blood lipid, correction of anemia, minerals - bone metabolic abnormalities, malnutrition, acid and alkali, and electrolyte disorder, diet and exercise, such as the guidance of integrated management, non intrusive, observational studies, prospective cohort were analyzed retrospectively, describe the implementation of the integration of diagnosis and treatment, chronic kidney disease (CKD) Stratified analysis and risk factor analysis were performed for cardiovascular disease and other main endpoint events, so as to objectively reflect the status of integrated treatment of CKD and provide data support for continuous quality improvement of CKD diagnosis and treatment and improvement of clinical prognosis of patients.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ≥18 years old;
• Voluntarily signed informed consent;
• Patients who are estimated to develop CKD.

Exclusion criteria

• Age < 18 or ≥100 years;
• Unable to comply with the procedures stipulated in this study;
• Estimated follow-up time ≤6 months.

Trial design

1,000 participants in 2 patient groups

Integrated group

Description:

Patients in the integrated group should be the patients getting integrated diagnosis and treatment during following up period. Integrated diagnosis and treatment includes control of hypertension, hyperglycemia, hyperlipidemia, anemia, CKD-MBD, and malnutrition by regular follow-up according to the guidelines of Kidney Disease- Improving Global Outcomes and of Chinese Medical Association in 2021.

Treatment:

Other: Integrated diagnosis and treatment for CKD

Unintegrated group

Description:

Patients in the unintegrated group are those who do not follow the contents of guidelines in some items of the integrated diagnosis and treatment during follow-up.

Treatment:

Other: Integrated diagnosis and treatment for CKD