Integrated Genetic and Functional Analysis of the Female Microbiome in a Flemish Cohort (Isala)

Antwerp University Hospital (UZA)

Status: Enrolling

Conditions: Skin Microbiome; Saliva Microbiome; Vaginal Microbiome

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04319536

B300201942076

Details and patient eligibility

About

The aim of the project is to improve our knowledge on the stability and temporal dynamics of the Flemish female microbiome (vagina, skin and saliva) in relation to different lifestyle factors and environmental conditions and to establish certain individual and social risk factors that can influence the healthy microbiome. Therefore, microbial DNA from swabs will be isolated via commercially available DNA extraction kits, followed by Illumina MiSeq sequencing in order to identify the microbial species present in these samples. Special attention will go to microbial species that are overrepresented in the healthy populations as potential health promoting microbes (i.e. probiotics).

Enrollment: 1,000 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• none

Exclusion criteria

• none

Trial design

1,000 participants in 1 patient group

Healthy individuals

Treatment:

Other: no intervention