Integrated RF and B-mode Deformation Analysis for 4D Stress Echocardiography

Yale University

Status: Withdrawn

Conditions: Coronary Artery Disease

Treatments: Procedure: Stress Dobutamine Echocardiographic using 4DE System

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT02327455

2R01HL121226-05A1 (U.S. NIH Grant/Contract)

R01HL0121226 (Other Grant/Funding Number)

1406014091

Details and patient eligibility

About

The specific aim of this clinical trial is to translate the investigators new 4DE (three sptial dimensions pluse time) stress echocardiographic method to patients with coronary artery disease referred for clinically indicated dobutamine stress/rest echo to evaluate the reproducibility of the technique in this clinical setting.

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• At least 18 years of age, referred for clinically indicated dobutamine rest/stress TTE
• Provide written informed consent to participate in the study
• Availability for repease rest/stress TTE within on eweek of clinically indicated study

Exclusion criteria

• Unable to give informed consent
• Unstable hemodynamics that would not allow for repease rest/stress dobutamine transthoracic imaging
• Recurrent life threatening arrhythmias
• Heart rate >110 BPM
• Inadequate windows for transthoracic imagine
• Patients that have a narrow-angle glaucoma (contraindication for atropine)
• Change in cardiac medications or management including, coronary revascularization beween intial and repeat TTE study.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

Stress Dobutamine Echocardiographic 4DE Image System

Experimental group

Description:

Subjects will undergo their clinically indicated stress dobutamine echocardiographic studies using our standard clinical graded dobutamine stress imaging protcol, employing the iE33 4DE system.

Treatment:

Procedure: Stress Dobutamine Echocardiographic using 4DE System